Search on: EPITHELIAL SODIUM CHANNEL 
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Descriptor English:   Epithelial Sodium Channel 
Descriptor Spanish:   Canal de Sodio Epitelial 
Descriptor Portuguese:   Canal Epitelial de Sódio 
Tree Number:   D12.776.157.530.400.875.500
D12.776.543.550.425.875.500
D12.776.543.585.400.875.500
Definition English:   An AMILORIDE-sensitive sodium channel found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON, the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. It plays a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE. 
History Note English:   2007(1995) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52323 
Unique Identifier:   D053503 

Occurrence in VHL:
 

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